red grapes

Grape Seed Extract – in a Nutshell

Why an Extract?

In natural foods there are components that promote health and fight disease. We mostly don’t eat enough natural stuff to get the full benefits, or our food is lacking because of the way it’s grown.

So we resort to extracts and concentrates that contain the “best” of a food’s chemicals. We usually choose our supplements to address a particular health concern. See below for up-to-date research results. 


Amongst other things, GSE contains proteins, lipids, carbohydrates and polyphenols (bioflavonoids). It’s a highly potent antioxidant – it protects the body against cellular damage. The antioxidant power of bioflavonoids is 20 times more powerful than vitamin E, and 50 times greater than vitamin C.

What is It Good For?

Unique ingredients help the body fight viruses, allergens, and carcinogens. That means that among their many talents, they exhibit anti-inflammatory, anti-allergic, anti-cancerous, anti-aging and anti-microbial activity.


This substance is found primarily in the red grape skin and seeds. It shows an ability to help the brain – i.e. neuroprotective capabilities. In rats, it has life-prolonging effects.


This was initially discovered in 1936 and called Vitamin P. It seems to  protect the body from premature ageing. Scientists think it increases vitamin C levels in the cells and scavenging for toxins. It also bonds with collagen, the most abundant protein in the body and a key component of skin, gums, bones, teeth, hair and body tissues. The bonding promotes cell health and skin elasticity.

Procyanidins additionally help protect the body from sun damage. They can also improve your vision, the flexibility of your joints, the health of your arteries and body tissues. 

Studies show they may have particular use against colorectal cancer.   Source

“Resveratrol News”

Bill Sardi of Resveratrol News believes it’s unfortunate that modern “medicine” will not put a natural product like resveratrol to the test in controlled human studies. 

Areas Where Resveratrol Shows Promise

  • Cardiology: not even one human pilot study has ensued. A lone cardiology group in Ft. Lee, New Jersey headed by Nate Lebowitz MD and Jacqueline Hollywood MD carries the lone torch for resveratrol. The unique method by which resveratrol works in the heart has now been validated in humans, not just the animal lab. [Clinical Hemorheol Microcirculation 2012] The most recent finding is that resveratrol via AMPK is capable of improving heart function. [Genetics Molecular Research Jan 21, 2014]
  • Cancer, Aging and Metabolic Problems: While there has been tremendous interest in resveratrol’s ability to control the Sirtuin1 survival genes however there is growing knowledge that resveratrol activates a cell energy-sensing molecule called AMPK that is at the center of aging, metabolic problems and even cancer. 
  • Haemorrhage: Resveratrol prolongs life of laboratory animals subjected to major injury accompanied by hemorrhage of blood. Instead of animals living 30 minutes they lived up to 4 hours when given resveratrol following major blood hemorrhage. [Molecular Medicine April 13, 2015] 
  • Concussions and other noise-induced brain trauma: It could be used on the battlefield to prevent and treat sports injuries and other accidental brain trauma. [Journal Trauma Acute Care Surgery Feb 2013] 
  • Fatty liver disease and hepatitis: Resveratrol could be used as front-line therapy given that more than a third of Americans have fatty liver disease. [Liver International June 16, 2015]
  • Diabetes: There is adequate human data for physicians to begin recommending resveratrol for diabetics. Resveratrol’s remarkably safety profile is also noted. [Molecular Nutrition Food Research Jan 2015]  “Resveratrol significantly improves glucose control and insulin sensitivity in persons with diabetes but does not affect glycemic measures in non-diabetic persons.” [American Journal Clinical Nutrition June 2014]
  • Eye conditions: About 15% of patients who suffer vision loss from macular degeneration do not respond to modern medicines injected directly into the eyes. Preliminary evidence points to resveratrol as a rescue agent. [Nutrients Oct 17, 2014] 
  • Prevention of Disease: Resveratrol exhibits profound ability to activate the body’s antioxidant enzymes glutathione, catalase and superoxide dismutase.  [Stroke June 2015; American Journal Physiology Regulation Integrative Complementary Physiology May 2015; Pharmacological Research Jan 2015; Redox Reports May 2014]